What we’re trying to learn
When someone faints repeatedly or feels lightheaded on standing, the most useful question is why. The two big mechanisms look similar at the bedside but call for different treatments:
- Vasovagal syncope — a reflex drop in blood pressure (sometimes with a heart-rate slowing) triggered by upright posture, emotional stress, pain, or dehydration. The drop reproduces the faint.
- Postural orthostatic tachycardia syndrome (POTS) — heart rate climbs by 30 beats per minute or more on standing (in adults) without a big drop in blood pressure. Patients feel breathless, foggy, and tachycardic but usually don’t lose consciousness.
- Orthostatic hypotension — a sustained blood-pressure drop on standing, often from medications, dehydration, or autonomic neuropathy.
A 12-lead ECG and a few minutes of standing in the office can hint at which pattern someone has, but tilt-table testing reproduces the response in a controlled environment with beat-to-beat monitoring — which is far more diagnostic than a guess.
How the test runs
You’ll be NPO from midnight (or for at least 4–6 hours). When you arrive, we place ECG leads, a continuous blood-pressure monitor (cuff or finger device that beats continuously), and IV access. You lie flat on a padded table with safety straps and a footboard for the feet to rest on.
The test moves through phases:
- Baseline (5–10 minutes flat). We make sure heart rate and blood pressure are stable.
- Passive tilt (up to 30–45 minutes at 60–70° upright). You stay still and we watch what happens. Most positive vasovagal responses occur in this phase.
- Provocation (optional, if passive tilt doesn’t reproduce symptoms). Either a small dose of sublingual nitroglycerin or a brief infusion of isoproterenol can unmask a response that the passive phase missed.
- Recovery. We tilt you back to flat, watch you stabilize, and end the test.
If you faint or come close to fainting, we lower the table immediately and your blood pressure recovers within a few minutes. Catching the event is the goal — it tells us what we’re treating.
What the test tells us — and what we do with it
- A vasovagal response points us toward salt, fluids, leg-crossing maneuvers, compression stockings, midodrine, and (less often) fludrocortisone. In rare carefully-selected patients with a strong cardio-inhibitory component, closed-loop stimulation pacing is considered.
- A POTS pattern opens the door to graded exercise reconditioning, fluid and salt expansion, beta-blockers or ivabradine, and sometimes midodrine. We also look hard at sleep, deconditioning, and underlying triggers (post-viral, autoimmune).
- Orthostatic hypotension prompts us to review medications first (antihypertensives, diuretics, antidepressants), then layer in non-pharmacologic measures and, when needed, midodrine or droxidopa.
- A negative tilt doesn’t mean nothing is wrong. It means the specific mechanism didn’t show up that day. If clinical suspicion is high, we look at other monitoring (implantable loop recorder) and revisit.
What patients tell us about it
The test isn’t painful, but it can feel intense — by design we’re trying to reproduce your worst symptom. We talk you through every phase. If you faint, you’re safely strapped in and we bring the table down immediately; recovery is quick. Most people leave the lab tired but relieved that we finally saw what they’d been describing.